Gary H Karpen Selected Research

Heterochromatin

1/2020	Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin.
10/2018	Heterochromatin: Guardian of the Genome.
1/2017	Phase separation drives heterochromatin domain formation.
1/2017	Drosophila Histone Demethylase KDM4A Has Enzymatic and Non-enzymatic Roles in Controlling Heterochromatin Integrity.
1/2016	A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin.
3/2011	Double-strand breaks in heterochromatin move outside of a dynamic HP1a domain to complete recombinational repair.

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Gary H Karpen Research Topics

Disease

8	Genomic Instability 01/2020 - 01/2007
5	Neoplasms (Cancer) 10/2018 - 06/2014
3	Carcinogenesis 10/2018 - 01/2017
1	Chromosomal Instability (Chromosome Stability) 01/2017
1	Breast Neoplasms (Breast Cancer) 06/2014
1	Neoplasm Metastasis (Metastasis) 06/2014
1	Hypersensitivity (Allergy) 03/2011

Drug/Important Bio-Agent (IBA)

6	HeterochromatinIBA 01/2020 - 03/2011
3	ChromatinIBA 01/2016 - 01/2007
2	Proteins (Proteins, Gene)FDA Link 01/2017 - 03/2011
2	CyclinsIBA 01/2017 - 01/2017
2	CytokinesIBA 03/2015 - 06/2014
2	RNA (Ribonucleic Acid)IBA 06/2014 - 03/2011
2	Histones (Histone)IBA 03/2011 - 03/2009
1	EuchromatinIBA 01/2017
1	Serine (L-Serine)FDA Link 01/2017
1	Centromere Protein AIBA 01/2017
1	DNA (Deoxyribonucleic Acid)IBA 01/2016
1	salicylhydroxamic acid (SHAM)IBA 03/2015
1	InterferonsIBA 06/2014
1	Deoxyribonuclease I (Nickase)IBA 03/2011
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 03/2011

Therapy/Procedure

1	Radiotherapy 01/2016
1	Drug Therapy (Chemotherapy) 01/2016
1	Therapeutics 01/2016
1	Transplantation 03/2015